抗人心肌肌钙蛋白 IC 复合物抗体对
01AB01049
The cardiac troponin I-C complex is a vital component in muscle contraction in both skeletal and cardiac muscle. This complex consists of three regulatory proteins: troponin C, troponin I, and troponin T. It plays a crucial role in detecting myocardial damage, with cardiac-specific troponins I and T being used as diagnostic and prognostic indicators for heart conditions. Elevated levels of cardiac troponins are sensitive and specific indicators of heart muscle damage, helping differentiate between unstable angina and myocardial infarction (heart attack). The stability of cTnI is significantly improved when it forms a complex with TnC or in a ternary complex with cTnT-TnC. Troponin is attached to tropomyosin in muscle tissue and, when stimulated by calcium, triggers muscle contraction by exposing binding sites for myosin on actin filaments. The cardiac troponin I-C complex is extensively used in immunoassays for detecting cTnI, aiding in the diagnosis and monitoring of heart conditions.
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技术参数
- 靶点基因名
- TNNI3&TNNC1
- 蛋白别名
- Troponin I, cardiac muscle&Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle&; cardiac troponin IC complex
- UniProt
- P19429 & P63316
- 物种
- Human
产品详情
- 靶点名称
- cardiac troponin IC complex
- 蛋白名称
- Troponin I, cardiac muscle&Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle&
- 靶点基因名
- TNNI3&TNNC1
- UniProt
- P19429 & P63316
- 来源物种
- /
背景介绍
The cardiac troponin I-C complex is a vital component in muscle contraction in both skeletal and cardiac muscle. This complex consists of three regulatory proteins: troponin C, troponin I, and troponin T. It plays a crucial role in detecting myocardial damage, with cardiac-specific troponins I and T being used as diagnostic and prognostic indicators for heart conditions. Elevated levels of cardiac troponins are sensitive and specific indicators of heart muscle damage, helping differentiate between unstable angina and myocardial infarction (heart attack). The stability of cTnI is significantly improved when it forms a complex with TnC or in a ternary complex with cTnT-TnC. Troponin is attached to tropomyosin in muscle tissue and, when stimulated by calcium, triggers muscle contraction by exposing binding sites for myosin on actin filaments. The cardiac troponin I-C complex is extensively used in immunoassays for detecting cTnI, aiding in the diagnosis and monitoring of heart conditions.