抗人癌胚抗原 CEA (CD66e) 抗体对
01AB03323
CEACAM5, also known as carcinoembryonic antigen (CEA), is a member of the CEACAM family of glycoproteins, characterized by its glycosylphosphatidylinositol (GPI) anchor and multiple immunoglobulin-like domains. This protein plays a crucial role in cell adhesion and is primarily expressed in the gastrointestinal tract, particularly in the colon. Its expression is significantly upregulated in various cancers, making it a valuable diagnostic and prognostic marker for colorectal cancer. CEACAM5 is involved in several physiological processes, including immune modulation and differentiation, and its dysregulation is associated with tumorigenesis and the progression of gastrointestinal diseases. Additionally, it serves as a receptor for certain pathogens, highlighting its importance in both health and disease contexts.
| 规格 | 起售价 |
|---|---|
| 登录后可查看 | |
技术参数
- 靶点基因名
- CEACAM5
- 基因别名
- CEA
- 蛋白别名
- CEA cell adhesion molecule 5; Carcino Embryonic Antigen CEA (CD66e)
- UniProt
- P06731
- 物种
- Human
产品详情
- 靶点名称
- Carcino Embryonic Antigen CEA (CD66e)
- 蛋白名称
- CEA cell adhesion molecule 5
- 蛋白别名
- Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD antigen CD66e
- 靶点基因名
- CEACAM5
- 基因别名
- CEA
- UniProt
- P06731
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
CEACAM5, also known as carcinoembryonic antigen (CEA), is a member of the CEACAM family of glycoproteins, characterized by its glycosylphosphatidylinositol (GPI) anchor and multiple immunoglobulin-like domains. This protein plays a crucial role in cell adhesion and is primarily expressed in the gastrointestinal tract, particularly in the colon. Its expression is significantly upregulated in various cancers, making it a valuable diagnostic and prognostic marker for colorectal cancer. CEACAM5 is involved in several physiological processes, including immune modulation and differentiation, and its dysregulation is associated with tumorigenesis and the progression of gastrointestinal diseases. Additionally, it serves as a receptor for certain pathogens, highlighting its importance in both health and disease contexts.