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人 CANT1 抗体对
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人 CANT1 抗体对

01AB04248

Calcium Activated Nucleotidase 1 (CANT1) is an enzyme encoded by the CANT1 gene located on chromosome 17q25.3 in humans. It is a soluble calcium-activated nucleotidase with a preference for UDP over other nucleotides like GDP, UTP, and GTP, and it has very low activity towards ADP and ATP. CANT1 is involved in proteoglycan synthesis and has been implicated in various diseases. Mutations in the CANT1 gene are associated with Desbuquois dysplasia, a rare skeletal disorder. Additionally, CANT1 has been found to be overexpressed in prostate cancer and plays a role in cell proliferation, migration, and invasion. The protein has a molecular weight of 44,839.24 Da and a theoretical pI of 6.082, with 401 residues.

Human
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技术参数

靶点基因名
CANT1
基因别名
SHAPY
蛋白别名
calcium activated nucleotidase 1; CANT1
UniProt
Q8WVQ1
物种
Human

产品详情

靶点名称
CANT1
蛋白名称
calcium activated nucleotidase 1
蛋白别名
Soluble calcium-activated nucleotidase 1; SCAN-1; Apyrase homolog; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107
靶点基因名
CANT1
基因别名
SHAPY
UniProt
Q8WVQ1
来源物种
Homo sapiens (Human)
物种反应性
Human

背景介绍

Calcium Activated Nucleotidase 1 (CANT1) is an enzyme encoded by the CANT1 gene located on chromosome 17q25.3 in humans. It is a soluble calcium-activated nucleotidase with a preference for UDP over other nucleotides like GDP, UTP, and GTP, and it has very low activity towards ADP and ATP. CANT1 is involved in proteoglycan synthesis and has been implicated in various diseases. Mutations in the CANT1 gene are associated with Desbuquois dysplasia, a rare skeletal disorder. Additionally, CANT1 has been found to be overexpressed in prostate cancer and plays a role in cell proliferation, migration, and invasion. The protein has a molecular weight of 44,839.24 Da and a theoretical pI of 6.082, with 401 residues.