人 CA5B 抗体对
01AB03953
Carbonic anhydrase 5B (CA5B) is a mitochondrial enzyme that catalyzes the reversible hydration of carbon dioxide to bicarbonate and protons, playing a crucial role in maintaining acid-base balance and facilitating respiratory gas exchange. It is characterized by its zinc-binding site, which is essential for its enzymatic activity, and its localization in the mitochondria, where it participates in various metabolic processes. Dysregulation or mutations in the CA5B gene have been associated with several diseases, particularly renal tubular acidosis, a condition characterized by the inability of the kidneys to excrete acids into the urine, leading to a systemic acid-base imbalance. Additionally, alterations in CA5B activity may contribute to metabolic disorders and conditions related to impaired mitochondrial function.
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技术参数
- 靶点基因名
- CA5B
- 蛋白别名
- carbonic anhydrase 5B; CA5B
- UniProt
- Q9Y2D0
- 物种
- Human
产品详情
- 靶点名称
- CA5B
- 蛋白名称
- carbonic anhydrase 5B
- 蛋白别名
- Carbonic anhydrase 5B; mitochondrial; Carbonate dehydratase VB; Carbonic anhydrase VB; CA-VB
- 靶点基因名
- CA5B
- UniProt
- Q9Y2D0
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Carbonic anhydrase 5B (CA5B) is a mitochondrial enzyme that catalyzes the reversible hydration of carbon dioxide to bicarbonate and protons, playing a crucial role in maintaining acid-base balance and facilitating respiratory gas exchange. It is characterized by its zinc-binding site, which is essential for its enzymatic activity, and its localization in the mitochondria, where it participates in various metabolic processes. Dysregulation or mutations in the CA5B gene have been associated with several diseases, particularly renal tubular acidosis, a condition characterized by the inability of the kidneys to excrete acids into the urine, leading to a systemic acid-base imbalance. Additionally, alterations in CA5B activity may contribute to metabolic disorders and conditions related to impaired mitochondrial function.