抗人 C1QTNF9 抗体对
01AB02795
C1q and TNF-related protein 9 (C1QTNF9), also known as CTRP9, is a secreted glycoprotein predominantly expressed in adipose tissue and cardiac endothelial cells. It plays a significant role in various physiological processes, including glucose and lipid metabolism, vasodilation, and inflammation regulation. CTRP9 activates key signaling pathways such as AMPK, AKT, and MAPK, which are crucial for maintaining metabolic homeostasis. Dysregulation of C1QTNF9 expression is associated with several diseases, particularly metabolic disorders like diabetes mellitus and diabetic cardiomyopathy. Studies indicate that CTRP9 has protective effects against inflammation and oxidative stress, enhancing insulin sensitivity and reducing cardiac dysfunction in diabetic models.
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技术参数
- 靶点基因名
- C1QTNF9
- 基因别名
- C1QTNF9A
- 蛋白别名
- C1q and TNF related 9; C1QTNF9
- UniProt
- P0C862
- 物种
- Human
产品详情
- 靶点名称
- C1QTNF9
- 蛋白名称
- C1q and TNF related 9
- 蛋白别名
- Complement C1q and tumor necrosis factor-related protein 9A; Complement C1q and tumor necrosis factor-related protein 9
- 靶点基因名
- C1QTNF9
- 基因别名
- C1QTNF9A
- UniProt
- P0C862
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
C1q and TNF-related protein 9 (C1QTNF9), also known as CTRP9, is a secreted glycoprotein predominantly expressed in adipose tissue and cardiac endothelial cells. It plays a significant role in various physiological processes, including glucose and lipid metabolism, vasodilation, and inflammation regulation. CTRP9 activates key signaling pathways such as AMPK, AKT, and MAPK, which are crucial for maintaining metabolic homeostasis. Dysregulation of C1QTNF9 expression is associated with several diseases, particularly metabolic disorders like diabetes mellitus and diabetic cardiomyopathy. Studies indicate that CTRP9 has protective effects against inflammation and oxidative stress, enhancing insulin sensitivity and reducing cardiac dysfunction in diabetic models.