人 C19orf53 抗体对
01AB00461
Chromosome 19 open reading frame 53 (C19orf53) known as Leydig cell tumor 10 kDa protein homolog. It belongs to the UPF0390 family and may have a potential role in hypercalcemia of malignancy. C19orf53 exhibits chaperone-like properties and has been identified as a "heat-resistant obscure" or "Hero" protein, displaying resilience and the ability to suppress pathological protein aggregation. It plays a role in mediating excessive cell proliferation, leading to metabolic imbalance and increased oxidative stress in response to toxins. Recent studies have associated C19orf53 with ischemic stroke risk, with genetic variations in the gene potentially influencing disease susceptibility. Additionally, C19orf53 has been implicated in various biological pathways, including rRNA biogenesis, ovarian cancer, and Zika virus replication.
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技术参数
- 靶点基因名
- C19orf53
- 蛋白别名
- chromosome 19 open reading frame 53; C19orf53
- UniProt
- Q9UNZ5
- 物种
- Human
产品详情
- 靶点名称
- C19orf53
- 蛋白名称
- chromosome 19 open reading frame 53
- 蛋白别名
- Leydig cell tumor 10 kDa protein homolog
- 靶点基因名
- C19orf53
- UniProt
- Q9UNZ5
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Chromosome 19 open reading frame 53 (C19orf53) known as Leydig cell tumor 10 kDa protein homolog. It belongs to the UPF0390 family and may have a potential role in hypercalcemia of malignancy. C19orf53 exhibits chaperone-like properties and has been identified as a "heat-resistant obscure" or "Hero" protein, displaying resilience and the ability to suppress pathological protein aggregation. It plays a role in mediating excessive cell proliferation, leading to metabolic imbalance and increased oxidative stress in response to toxins. Recent studies have associated C19orf53 with ischemic stroke risk, with genetic variations in the gene potentially influencing disease susceptibility. Additionally, C19orf53 has been implicated in various biological pathways, including rRNA biogenesis, ovarian cancer, and Zika virus replication.