人 BMPR1B 抗体对
01AB03644
Bone Morphogenetic Protein Receptor Type 1B (BMPR1B) is a transmembrane serine/threonine kinase receptor that plays a crucial role in the bone morphogenetic protein (BMP) signaling pathway. It is involved in various biological processes, including embryogenesis, tissue homeostasis, and disease progression. BMPR1B is predominantly expressed in embryonic tissues, skeletal structures, and reproductive organs, and it signals through Smad-dependent and Smad-independent pathways to regulate gene expression, cellular proliferation, differentiation, and apoptosis. Mutations in the BMPR1B gene have been associated with several diseases, including acromesomelic dysplasia, brachydactyly type A1, and primary pulmonary hypertension.
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技术参数
- 靶点基因名
- BMPR1B
- 蛋白别名
- bone morphogenetic protein receptor type 1B; BMPR1B
- UniProt
- O00238
- 物种
- Human
产品详情
- 靶点名称
- BMPR1B
- 蛋白名称
- bone morphogenetic protein receptor type 1B
- 蛋白别名
- Bone morphogenetic protein receptor type-1B; BMP type-1B receptor; BMPR-1B; CD antigen CDw293
- 靶点基因名
- BMPR1B
- UniProt
- O00238
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Bone Morphogenetic Protein Receptor Type 1B (BMPR1B) is a transmembrane serine/threonine kinase receptor that plays a crucial role in the bone morphogenetic protein (BMP) signaling pathway. It is involved in various biological processes, including embryogenesis, tissue homeostasis, and disease progression. BMPR1B is predominantly expressed in embryonic tissues, skeletal structures, and reproductive organs, and it signals through Smad-dependent and Smad-independent pathways to regulate gene expression, cellular proliferation, differentiation, and apoptosis. Mutations in the BMPR1B gene have been associated with several diseases, including acromesomelic dysplasia, brachydactyly type A1, and primary pulmonary hypertension.