人 BD-pTau217 抗体对
01AB00064
BD-pTau217 is a brain-derived form of the tau protein phosphorylated at the threonine-217 residue, serving as a highly specific blood-based biomarker for neurodegenerative pathology. This assay specifically targets central nervous system-enriched pTau217 to minimize interference from peripheral tau sources, allowing for the precise measurement of tau pathology from plasma or serum samples. The protein is a key indicator of the microtubule disruption and axonal transport failure associated with hyperphosphorylated tau accumulation. It is primarily utilized in the early detection and differential diagnosis of Alzheimer's disease, offering significant diagnostic performance that correlates closely with cognitive decline and disease progression in clinical research settings.
| 规格 | 起售价 |
|---|---|
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技术参数
- 靶点基因名
- MAPT
- 基因别名
- MAPTL; MTBT1; TAU
- 蛋白别名
- Microtubule-associated protein tau; BD-pTau217
- UniProt
- P10636-8
- 物种
- Human
产品详情
- 靶点名称
- BD-pTau217
- 蛋白名称
- Microtubule-associated protein tau
- 靶点基因名
- MAPT
- 基因别名
- MAPTL; MTBT1; TAU
- UniProt
- P10636-8
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
BD-pTau217 is a brain-derived form of the tau protein phosphorylated at the threonine-217 residue, serving as a highly specific blood-based biomarker for neurodegenerative pathology. This assay specifically targets central nervous system-enriched pTau217 to minimize interference from peripheral tau sources, allowing for the precise measurement of tau pathology from plasma or serum samples. The protein is a key indicator of the microtubule disruption and axonal transport failure associated with hyperphosphorylated tau accumulation. It is primarily utilized in the early detection and differential diagnosis of Alzheimer's disease, offering significant diagnostic performance that correlates closely with cognitive decline and disease progression in clinical research settings.