人 ATG10 抗体对
01AB04231
Autophagy related 10 (ATG10) is a protein crucial for autophagy, a cellular process that degrades and recycles cellular components. ATG10 acts as an E2-like enzyme, facilitating the conjugation of ATG12 to ATG5, which is essential for autophagosome formation. It is involved in various biological processes, including the regulation of dsDNA-induced innate immune responses and the suppression of HCV replication by promoting complete autophagy. The protein has two isoforms, ATG10 and ATG10S, which differ by a 36-amino acid fragment and exhibit distinct effects on HCV replication and autophagy flux. ATG10 is also implicated in adenovirus-mediated cell lysis and has roles in cancer cell invasion and proliferation, as well as bacterial infections.
| 规格 | 起售价 |
|---|---|
| 登录后可查看 | |
技术参数
- 靶点基因名
- ATG10
- 基因别名
- APG10L
- 蛋白别名
- autophagy related 10; ATG10
- UniProt
- Q9H0Y0
- 物种
- Human
产品详情
- 靶点名称
- ATG10
- 蛋白名称
- autophagy related 10
- 蛋白别名
- Ubiquitin-like-conjugating enzyme ATG10; Autophagy-related protein 10; APG10-like
- 靶点基因名
- ATG10
- 基因别名
- APG10L
- UniProt
- Q9H0Y0
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Autophagy related 10 (ATG10) is a protein crucial for autophagy, a cellular process that degrades and recycles cellular components. ATG10 acts as an E2-like enzyme, facilitating the conjugation of ATG12 to ATG5, which is essential for autophagosome formation. It is involved in various biological processes, including the regulation of dsDNA-induced innate immune responses and the suppression of HCV replication by promoting complete autophagy. The protein has two isoforms, ATG10 and ATG10S, which differ by a 36-amino acid fragment and exhibit distinct effects on HCV replication and autophagy flux. ATG10 is also implicated in adenovirus-mediated cell lysis and has roles in cancer cell invasion and proliferation, as well as bacterial infections.