人 ARAP3 抗体对
01AB00450
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 (ARAP3) is a protein that plays a crucial role in modulating actin cytoskeleton remodeling by regulating ARF and RHO family GTPases. It is a phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that is implicated in phosphoinositide 3-kinase (PI 3-kinase) signaling pathways. The protein contains multiple domains including ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains, which enable it to interact with various signaling molecules. ARAP3 is expressed in various tissues, including the brain, thyroid gland, lung, and others, indicating its widespread involvement in cellular processes. Its role in PI 3-kinase signaling pathways suggests potential implications in diseases related to cell signaling and cytoskeleton regulation.
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技术参数
- 靶点基因名
- ARAP3
- 基因别名
- CENTD3
- 蛋白别名
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3; ARAP3
- UniProt
- Q8WWN8
- 物种
- Human
产品详情
- 靶点名称
- ARAP3
- 蛋白名称
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
- 蛋白别名
- Arf-GAP with Rho-GAP domain; ANK repeat and PH domain-containing protein 3; Centaurin-delta-3; Cnt-d3
- 靶点基因名
- ARAP3
- 基因别名
- CENTD3
- UniProt
- Q8WWN8
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 (ARAP3) is a protein that plays a crucial role in modulating actin cytoskeleton remodeling by regulating ARF and RHO family GTPases. It is a phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that is implicated in phosphoinositide 3-kinase (PI 3-kinase) signaling pathways. The protein contains multiple domains including ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains, which enable it to interact with various signaling molecules. ARAP3 is expressed in various tissues, including the brain, thyroid gland, lung, and others, indicating its widespread involvement in cellular processes. Its role in PI 3-kinase signaling pathways suggests potential implications in diseases related to cell signaling and cytoskeleton regulation.