抗人 APBB1IP 抗体对
01AB03935
Amyloid beta precursor protein binding family B member 1 interacting protein (APBB1IP), also known as Rap1-GTP-interacting adapter molecule (RIAM), is a protein encoded by the APBB1IP gene in humans. It plays a crucial role in signal transduction from Ras activation to actin cytoskeletal remodeling and suppresses insulin-induced promoter activities through AP1 and SRE. APBB1IP is a phospholipid-binding protein that functions in the p130Cas linkage to MAPK signaling for integrins and platelet aggregation pathways. Its involvement in T cell activation via T cell receptor contact with antigen bound to MHC molecules on antigen-presenting cells further underscores its diverse biological roles. APBB1IP is involved in mediating Rap1-induced adhesion and is associated with diseases such as Alzheimer's disease and melanoma.
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技术参数
- 靶点基因名
- APBB1IP
- 基因别名
- PREL1; RARP1; RIAM
- 蛋白别名
- amyloid beta precursor protein binding family B member 1 interacting protein; APBB1IP
- UniProt
- Q7Z5R6
- 物种
- Human
产品详情
- 靶点名称
- APBB1IP
- 蛋白名称
- amyloid beta precursor protein binding family B member 1 interacting protein
- 蛋白别名
- Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; APBB1-interacting protein 1; Proline-rich EVH1 ligand 1; PREL-1; Proline-rich protein 73; Rap1-GTP-interacting adapter molecule; RIAM; Retinoic acid-responsive proline-rich protein 1; RARP-1
- 靶点基因名
- APBB1IP
- 基因别名
- PREL1; RARP1; RIAM
- UniProt
- Q7Z5R6
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Amyloid beta precursor protein binding family B member 1 interacting protein (APBB1IP), also known as Rap1-GTP-interacting adapter molecule (RIAM), is a protein encoded by the APBB1IP gene in humans. It plays a crucial role in signal transduction from Ras activation to actin cytoskeletal remodeling and suppresses insulin-induced promoter activities through AP1 and SRE. APBB1IP is a phospholipid-binding protein that functions in the p130Cas linkage to MAPK signaling for integrins and platelet aggregation pathways. Its involvement in T cell activation via T cell receptor contact with antigen bound to MHC molecules on antigen-presenting cells further underscores its diverse biological roles. APBB1IP is involved in mediating Rap1-induced adhesion and is associated with diseases such as Alzheimer's disease and melanoma.