抗人 alpha-1-Fetoprotein 抗体对
01AB03817
Alpha-fetoprotein (AFP) is a glycoprotein primarily produced by the fetal liver, yolk sac, and gastrointestinal tract during pregnancy. It plays a crucial role in fetal development, with levels peaking in the fetal serum around 12 to 14 weeks of gestation and in maternal serum between 28 to 32 weeks. After birth, AFP levels drop significantly and are typically low in healthy adults. Clinically, AFP serves as a tumor marker, particularly for liver cancer, testicular cancer, and certain ovarian cancers. Elevated AFP levels can indicate various conditions, including liver diseases like cirrhosis and hepatocellular carcinoma, making it a valuable tool for diagnosing and monitoring treatment responses in cancer patients. Additionally, abnormal AFP levels during pregnancy can signal potential fetal abnormalities, such as neural tube defects.
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技术参数
- 靶点基因名
- AFP
- 基因别名
- HPAFP
- 蛋白别名
- alpha fetoprotein; alpha-1-Fetoprotein
- UniProt
- P02771
- 物种
- Human
产品详情
- 靶点名称
- alpha-1-Fetoprotein
- 蛋白名称
- alpha fetoprotein
- 蛋白别名
- Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
- 靶点基因名
- AFP
- 基因别名
- HPAFP
- UniProt
- P02771
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Alpha-fetoprotein (AFP) is a glycoprotein primarily produced by the fetal liver, yolk sac, and gastrointestinal tract during pregnancy. It plays a crucial role in fetal development, with levels peaking in the fetal serum around 12 to 14 weeks of gestation and in maternal serum between 28 to 32 weeks. After birth, AFP levels drop significantly and are typically low in healthy adults. Clinically, AFP serves as a tumor marker, particularly for liver cancer, testicular cancer, and certain ovarian cancers. Elevated AFP levels can indicate various conditions, including liver diseases like cirrhosis and hepatocellular carcinoma, making it a valuable tool for diagnosing and monitoring treatment responses in cancer patients. Additionally, abnormal AFP levels during pregnancy can signal potential fetal abnormalities, such as neural tube defects.