人 ADGRF2P 抗体对
01AB02925
Adhesion G protein-coupled receptor F2 (ADGRF2P) is a member of the adhesion GPCR family, characterized by a large extracellular region containing adhesion-like motifs and a GPCR Autoproteolysis Inducing (GAIN) domain. Predicted to possess seven transmembrane helices and G protein-coupled signaling activity, it represents an orphan receptor with undefined ligands. Although the locus is annotated as a pseudogene in some reference databases, it retains coding potential for a functional membrane protein. Emerging genetic studies link the ADGRF2 locus to complex cortical dysplasias and brain malformations, suggesting a role in neurodevelopmental signaling and cortical architecture organization.
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技术参数
- 靶点基因名
- ADGRF2P
- 基因别名
- ADGRF2; GPR111; PGR20
- 蛋白别名
- adhesion G protein-coupled receptor F2, pseudogene; ADGRF2P
- UniProt
- Q8IZF7
- 物种
- Human
产品详情
- 靶点名称
- ADGRF2P
- 蛋白名称
- adhesion G protein-coupled receptor F2, pseudogene
- 蛋白别名
- Putative adhesion G protein-coupled receptor F2P; Adhesion G-protein coupled receptor F2; G-protein coupled receptor 111; G-protein coupled receptor PGR20
- 靶点基因名
- ADGRF2P
- 基因别名
- ADGRF2; GPR111; PGR20
- UniProt
- Q8IZF7
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
Adhesion G protein-coupled receptor F2 (ADGRF2P) is a member of the adhesion GPCR family, characterized by a large extracellular region containing adhesion-like motifs and a GPCR Autoproteolysis Inducing (GAIN) domain. Predicted to possess seven transmembrane helices and G protein-coupled signaling activity, it represents an orphan receptor with undefined ligands. Although the locus is annotated as a pseudogene in some reference databases, it retains coding potential for a functional membrane protein. Emerging genetic studies link the ADGRF2 locus to complex cortical dysplasias and brain malformations, suggesting a role in neurodevelopmental signaling and cortical architecture organization.