抗人 ADAMTS15 抗体对
01AB00642
ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15) is a member of the ADAMTS family, which consists of 19 secreted zinc metalloproteases. It is involved in various biological processes, including modulation of cell-extracellular matrix interactions, which are crucial in tumor pathophysiology. The protein exhibits proteolytic activity against the proteoglycan VCAN. ADAMTS15 is expressed in multiple tissues, including cytoplasmic expression in most tissues and additional luminal membrane expression in the gastrointestinal tract. It has been identified as a candidate gene for intracranial aneurysms, suggesting a potential role in vascular diseases. Overall, ADAMTS15 plays a significant role in extracellular matrix remodeling and may contribute to various pathological conditions.
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技术参数
- 靶点基因名
- ADAMTS15
- 蛋白别名
- ADAM metallopeptidase with thrombospondin type 1 motif 15; ADAMTS15
- UniProt
- Q8TE58
- 物种
- Human
产品详情
- 靶点名称
- ADAMTS15
- 蛋白名称
- ADAM metallopeptidase with thrombospondin type 1 motif 15
- 蛋白别名
- A disintegrin and metalloproteinase with thrombospondin motifs 15; ADAM-TS 15; ADAM-TS15; ADAMTS-15
- 靶点基因名
- ADAMTS15
- UniProt
- Q8TE58
- 来源物种
- Homo sapiens (Human)
- 物种反应性
- Human
背景介绍
ADAM metallopeptidase with thrombospondin type 1 motif 15 (ADAMTS15) is a member of the ADAMTS family, which consists of 19 secreted zinc metalloproteases. It is involved in various biological processes, including modulation of cell-extracellular matrix interactions, which are crucial in tumor pathophysiology. The protein exhibits proteolytic activity against the proteoglycan VCAN. ADAMTS15 is expressed in multiple tissues, including cytoplasmic expression in most tissues and additional luminal membrane expression in the gastrointestinal tract. It has been identified as a candidate gene for intracranial aneurysms, suggesting a potential role in vascular diseases. Overall, ADAMTS15 plays a significant role in extracellular matrix remodeling and may contribute to various pathological conditions.