抗人 HLA-DR, DP, DQ 抗体（PerCP-Vio® 700 标记，REAfinity™）

01MT00428

Clone REA332 recognizes all major histocompatibility class (MHC) class II HLA-DR, DP, and most DQ antigens. Expressed on the surface of most nucleated cells, MHC class II molecules play an important role in the immune system. They are essential in the defense against infection and are a main consideration in transplantation medicine. In addition to presenting antigenic peptides from predominantly extracellular sources to CD4+ T cells, MHC class II molecules also mediate the thymic selection of T helper cells. MHC class II molecules consist of an α and β chain and are transported to endosomal-l