HLA-DR Antibody, anti-human, APC, REAfinity™

01MT05616

Clone REA805 recognizes the human major histocompatibility (MHC) class II antigen HLA-DR, a heterodimeric cell surface glycoprotein belonging to the Ig superfamiliy. HLA-DR is constitutively expressed on professional antigen-presenting cells like dendritic cells, B cells, and monocytes/macrophages. Its expression is further up-regulated upon activation. On T cells, natural killer (NK) cells, hematopoietic precursor cells, and some epithelial cells the expression of HLA-DR is induced by cell activation.Additional information: Clone REA805 displays negligible binding to Fc receptors.