Histone H3.3 抗体，抗人，FITC，REAfinity™

01MT00144

Clone REA1507 recognizes the a histone variant Histone H3.3, which is enriched at actively transcribed genes, enhancers, as well as heterochromatic regions like telomeres and centromeres. In neural stem cells, Histone H3.3 is important for balanced proliferation and differentiation. During spermatogenesis, Histone H3.3 is crucial for chromatin reorganization. It is involved in transcriptional regulation, chromatin structure, developement, fertility, aging, and is implicated in cancer through specific mutations.