Histone H3 (tri-methyl-K27) Antibody, anti-human, PE, REAfinity™

01MT14086

Clone REA1493 recognizes Histone H3 (tri-methyl-K27), which is a epigeneitic modification where three methylgroups are added to lysine 27 of histone H3. It is catalyzed by the enzyme EZH2 within the Polycomb Repressive Complex 2 (PCR2) and leads to gene silencing by compacting chromatin. This modification plays a key role in cell differentiation, development, and is often dysregulated in cancer.