H60a Antibody, anti-mouse, APC, REAfinity™

01MT04756

Clone REA556 recognizes the mouse H60a antigen, a histocompatibility antigen expressed in BALB but not C57BL/6 mouse strains. H60a is expressed on haematopoietic cells and is also is found on tumor cells that constitutively express H60a at the cell surface. H60a is recognized by H60a-specific CD8+ T cells. H60a also binds natural killer group 2, member D (NKG2D) and can participate in tumor surveillance and cancer immunoediting. H60a is up-regulated by certain stimuli including DNA damage and virus infection.Additional information: Clone REA556 displays negligible binding to Fc receptors.