GUCY2C Antibody, anti-human, Vio® B515, REAdye_lease™

01MT13827

Clone REAL1624 is an antibody fragment derived from the full GUCY2C antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.Clone REAL1624 recognizes GUCY2C, also known as Guanylyl cyclase C that catalyzes synthesis of cyclic GMP (cGMP) from GTP. It functions as a key receptor for heat-stable enterotoxins that are responsible for acute secretory diarrhea. GUCY2C is found in the luminal aspect of intestinal epithelium and dopamine neurons in the brain and is the