GATA3 Antibody, anti-human/mouse, FITC, REAfinity™

01MT04463

Clone REA174 recognizes GATA3, a member of the GATA family of transcription factors. Like other members of the family, GATA3 contain zinc finger motifs involved in recognizing the canonical GATA DNA sequence. GATA3 has two trans-activating domains and two zinc finger domains, each followed by a conserved basic region. Expression of GATA3 is found in developing and mature T cells, natural killer (NK) cells, subset of NKT cells, and endothelial cells. Primary function attributed to GATA3 is to regulate the T helper 2 (Tʜ2) cell differentiation. However, role of GATA3 is also recognized in early