GATA3 Antibody, anti-human, APC, REAfinity™

01MT13881

Clone REA1405 recognizes human GATA3, a member of the GATA family of transcription factors. Like other members of the family, GATA3 contain zinc finger motifs involved in recognizing the canonical GATA DNA sequence. GATA3 has two trans-activating domains and two zinc finger domains, each followed by a conserved basic region. GATA3 functions as an important regulator of T-cell development and plays a role in embryonic development and in endothelial cell biology. Expression of GATA3 is found in developing and mature T cells, natural killer (NK) cells, subset of NKT cells, and endothelial cells.