FoxA2 Antibody, anti-human, pure, REAfinity™

01MT04998

Clone REA506 recognizes the human forkhead box A2 (FoxA2) antigen, a transcription factor which is also known as hepatocyte nuclear factor 3β (HNF-3β). FoxA2 is involved in embryonic development, establishment of tissue-specific gene expression, and regulation of gene expression in differentiated tissues. It is thought to act as a pioneer factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. In embryonic development, FoxA2 is required for notochord formation.