FcRL6 Antibody, anti-human, PE, REAfinity™

01MT14007

Clone REA1392 recognizes rhe human FcRL6 (FcR-like protein 6), a Type I transmembrane glycoprotein of the Ig gene superfamily and acts as a MHC class II receptor. It is expressed by cytolytic cells including NK cells, effector and effector-memory CD8+ T cells, and a subset of NKT cells. Its expression level correlates with the differentiation state of these cells. Also expressed in gamma delta T cells and in a rare subset of effector CD4+ T cells. Expression is higher in PBMCs of patients with HIV-1 infection, autoimmune diseases and chronic lymphocytic leukemia (CLL) but is reduced in PBMCs