ErbB-2 (CD340) Antibody, anti-human, APC

01MT17364

Clone 24D2 recognizes the human receptor tyrosine-protein kinase ErbB-2 antigen, a single-pass type I membrane protein which is also known as CD340, human epidermal growth factor receptor 2 (Her2), or proto-oncogene Neu. ErbB-2 is a member of the epidermal growth factor receptor family. The ErbB family is composed of four plasma membrane-bound receptor tyrosine kinases. All four contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular domain that can interact with a multitude of signaling molecules and exhibit both ligand-dependent and ligand-independent act