Enolase 2 (NSE) Antibody, anti-human, PE, REAfinity™

01MT13861

Clone REA1402 recognizes the human Enolase 2 (NSE) homodimeric protein, an isoenzyme which is detected in mature neurons. Furthermore, NSE is produced by cells with neuroendocrine differentiation. NSE is a phosphopyruvate hydratase with several funtions in the central nervous system (CNS), e.g. promotion of cell survival. NSE is a positive tumormarker for small cell carcinomas which are neuroendocrine in origin, including lung cancer. REA1402 does not react with the alpha or beta isoenzymes of enolase.Additional information: Clone REA1402 displays negligible binding to Fc receptors.