EGFRvIII Antibody, anti-human, PE, REAfinity™

01MT13781

The epidermal growth factor receptor (EGFR) is a single-pass type I membrane protein which is also known as receptor tyrosine-protein kinase ErbB-1 or HER1. EGFR is ubiquitously expressed in normal cells and overexpressed in many tumor cell lines. It is a critical regulator of many normal cellular processes, including cell growth, differentiation, survival, and migration. The EGFR is also implicated in pathological processes of cellular transformation and oncogenesis due to its overexpression in many types of cancers and its ability to induce morphological transformation of cultured cells and