EGF Receptor pY1173 Antibody, anti-human, APC, REAfinity™

01MT05797

Clone REA696 recognizes the human epidermal growth factor receptor (EGFR) antigen phosphorylated at tyrosine 1173 (pY1173). EGFR is a single-pass type I membrane protein which is also known as receptor tyrosine-protein kinase ErbB-1 or HER1. It is a critical regulator of many normal cellular processes, including cell growth, differentiation, survival, and migration. The EGFR is also implicated in pathological processes of cellular transformation and oncogenesis due to its overexpression in many types of cancers and its ability to induce morphological transformation of cultured cells and tumor