EGF Receptor pY1068 Antibody, anti-human, APC, REAfinity™

01MT05149

Clone REA644 recognizes the human epidermal growth factor receptor (EGFR) antigen phosphorylated at tyrosine 1068 (pY1068). EGFR is a single-pass type I membrane protein which is also known as receptor tyrosine-protein kinase ErbB-1 or HER1. It is a critical regulator of many normal cellular processes, including cell growth, differentiation, survival, and migration. The EGFR also is implicated in pathological processes of cellular transformation and oncogenesis due to its overexpression in many types of cancers and its ability to induce morphological transformation of cultured cells and tumor