DAB2 Antibody, anti-human, Vio® B515, REAdye_lease™

01MT13799

Clone REAL1215 is an antibody fragment derived from the full DAB2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.Clone REAL1215 recognizes the DAB2 adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. Down-regulation of DAB2 may play a