Cytokeratin 17 Antibody, anti-human, APC, REAfinity™

01MT14074

Clone REA1495 recognizes the Cytokeratin 17 Cytokeratins, which are found in almost all epithelial cells.Keratins are polypeptides with keratin-containing intermediate filaments, which ensure form stability and cohesiveness. Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions and are involved in intracellular signaling pathways. Keratin 17, a type I cytokeratin, is located in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in the gene encoding this protein lead to PC-K17 (previousl