CXCL10 (IP-10) Antibody, anti-human, Vio® B515, REAfinity™

01MT03141

Clone REA334 recognizes the human C-X-C motif chemokine 10 (CXCL10) antigen, a secreted molecule also known as interferon gamma-induced protein (IP-10). CXCL10 is a member of the CXC chemokine family which binds to the cell surface chemokine receptor CXCR3 to exert its biological effects. It is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells, and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial