CX3CL1 Antibody, anti-human, APC, REAfinity™

01MT04304

Clone REA281 recognizes the human C-X3-C motif chemokine 1 (CX3CL1) antigen, a single-pass type I membrane protein, which is also known as fractalkine or neurotactin. CX3CL1 is expressed in a number of cell types including neurons, intestinal epithelium, and activated vascular endothelium and is structurally distinct from other chemokines. The membrane-anchored form of CX3CL1 induces tight, shear-resistant endothelial adhesion of leukocytes in a manner that is independent of integrin and Gi protein activation. Soluble forms of CX3CL1 generated by proteolytic cleavage with the disintegrin and m