CREB pS133/ATF1 pS63 Antibody, anti-human, PE, REAfinity™

01MT02395

Clone REA131 recognizes the serine 133 (S133)–phosphorylated form of the human cAMP responsive element (CRE)–binding transcription factor CREB, a member of a family of cAMP responsive element (CRE)–binding transcription factors that include CREB, CRE modulator (CREM), and activating transcription factor 1 (ATF1). REA131 cross-reacts with the S63-phosphorylated form of human ATF-1. Several different serine-threonine kinases have been shown to promote phosphorylation of CREB at its transcription activating site, S133, including a cAMP-dependent protein kinase A (PKA), protein kinase C (PKC; incl