Claudin-3 Antibody, anti-human, PE, REAfinity™

01MT06973

Clone REA751 recognizes the human claudin-3 antigen, an integral membrane protein which is a component of the claudin family of epithelial tight junction proteins. Claudin-3 is involved in tight junction-specific obliteration of the intercellular space. It is a low-affinity receptor for Clostridium perfringens enterotoxinin (CPE). Binding of CPE to claudin-3 induces epithelial cell lysis.Additional information: Clone REA751 displays negligible binding to Fc receptors.