CD8a Antibody, anti-mouse, APC, REAfinity™

01MT10401

Clone REA601 is specific for the mouse CD8a antigen, also known as LY-2 or T8, which is expressed on cytotoxic T cells and at lower levels on subpopulations of dendritic cells and TCRγ/δ+ cells. CD8a is further detected on most thymocytes (CD4+CD8a+ and CD4–CD8+ thymocytes). Cytotoxic T cells and thymocytes express CD8a as heterodimer with CD8b, whereas dendritic cells and TCRγ/δ+ cells express a CD8a/CD8a homodimer. It mediates efficient cell-cell interactions within the immune system.Additional information: Clone REA601 displays negligible binding to Fc receptors.