CD8a Antibody, anti-human, APC, REAfinity™

01MT12123

Clone REA1024 recognizes the human CD8 antigen, a cell-surface glycoprotein, also known as Leu-2 or CD8a. CD8 is strongly expressed on human cytotoxic T cells and thymocytes, and on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8a homodimer or as a CD8α/β heterodimer. CD8 acts as a coreceptor for the T cell receptor and binds to the MHC Class I molecules. CD8 is involved in T cell development and activation of mature T cells. The CD8 antibody recognizes the α-subunit of the antigen.Additional information: Clone REA1024 displays negligible binding t