CD85h (ILT1) Antibody, anti-human, APC, REAfinity™

01MT01679

Clone REA219 recognizes CD85h (ILT1), a member of the immunoglobulin-like transcripts (ILT) family of proteins. ILT family members compose of both activating and inhibitory receptors, where CD85h serves as an activating receptor. In contrast to inhibitory members, CD85h posesses a positively charged amino acid in its trasmembrane domain and a short cytoplasmic domain which is devoid of sequence motifs involved in signal transduction. To transduce activating signal, ILT1 forms a multiprotein complex with FCεRIγ. Expression of ILT1 is found on the surface of monocytes/macrophages, dendritic cell