CD84 Antibody, anti-mouse, APC, REAfinity™

01MT01665

Clone REA212 recognizes murine CD84, a type I transmembrane glycoprotein belonging to the SLAM (CD150) family, a CD2 subset of the Ig superfamily of cell-surface receptors. Genes encoding for SLAM members are located on the syntenic region of mouse chromosome 1 and these receptors play vital role in regulation of innate and adaptive immune responses. CD84, like other SLAM receptors has an extracellular ectodomain formed by two Ig-like domains and a cytoplasmic domain with 2 copies of the ITSM (T-I/V-Y-x-x-V/I) motif, which is a docking site for SH2-binding phosphatases and the adaptor molecule