CD84 Antibody, anti-human, APC

01MT15124

Human CD84 is a 65–80 kDa single-chain surface glycoprotein and member of the CD2 subset of the immunoglobulin (Ig) superfamily. CD84 is expressed on granulocytes, monocytes, macrophages, B cells, platelets, antigen-presenting cells, and subsets of T cells including thymocytes and mature T cells. Homophilic ligation of CD84 or ligation with CD84 antibodies has been shown to lead to enhanced proliferation of T cells as well as IFN-γ secretion. CD84 thus serves as a co-stimulatory molecule. CD84 gene expression has also been detected in lung and kidney tissue as well as on hematopoietic progenit