CD8 Antibody, anti-human, PE

01MT18393

Clone BW135/80 Fab recognizes the human CD8 antigen which is strongly expressed on human cytotoxic T cells and thymocytes, and is also expressed on a subset of NK cells. The CD8 antigen is a disulfide-linked dimer that exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8 acts as a co-receptor for the T cell receptor and binds to the MHC class I molecule. The CD8 antibody recognizes the α-subunit of the antigen. Clone BW135/80 Fab is a clone BW135/80-derived Fab fragment of the full antibody molecule.Additional information: Clone BW135/80 Fab displays negligible binding to Fc recep