CD68 Antibody, anti-human, APC

01MT16591

The monoclonal antibody Y1/82A reacts with CD68, a 110 kDa type I transmembrane glycoprotein classified as a lysosomal/endosomal-associated membrane glycoprotein (LAMP) family member. CD68 is highly expressed by human monocytes and tissue macrophages but also found in subpopulations of B cells, fibroblasts, endothelial, and other cells. It is found predominantely in late endosomal and lysosomal compartments, with a modest level of cell surface expression. CD68 is suggested to be involved in phagocytic activities of tissue macrophages, in intracellular lysosomal metabolism, and extracellular ce