CD63 Antibody, anti-human, APC, REAfinity™

01MT10998

Clone REA1055 recognizes the human CD63 antigen, a type III glycoprotein belonging to the tetraspanin family of proteins, which are characterized by four membrane spanning domains. Tetraspanins via various homotypic and heterotypic interactions regulate the spatial location and trafficking of associated transmembrane partners, eventually regulating and co-ordinating various signaling pathways. CD63, like other tetraspanins, is present in the plasma membrane and membrane of various subcellular compartments such as late endosomes, lysososmes, cytotoxic granules of T lymphocytes, the crystalloid