CD48 Antibody, anti-human, APC, REAfinity™

01MT00919

Clone REA426 recognizes the human CD48 antigen, a glycosyl-phosphatidyl-inositol (GPI)-anchored cell-surface protein of the CD2 family of molecules, which is also known as B-lymphocyte activation marker BLAST-1, BCM1, MEM-102, or SLAM family member 2 (SLAMF2). CD48 is expressed on various hematopoietic cells and its expression is regulated by viral and bacterial products and immune-associated proteins. CD48 binds CD2 and other molecules, yet its high-affinity ligand in both mouse and human systems is CD244 (2B4). Despite its lack of an intracellular domain, stimulation of CD48 induces rearrang