CD45RC Antibody, anti-human, APC, REAfinity™

01MT13888

Clone REA1271 recognizes the CD45RC isoforms of the human CD45 antigen, a member of the protein tyrosine phosphatase (PTP) family, also known as the leukocyte common antigen (LCA). The CD45 molecule is a type I transmembrane protein which is required for T and B cell activation and involved in cell growth, differentiation, mitotic cycle, and oncogenic transformation.CD45RC is expressed on medullary thymocytes, CD8+ T cells, B cells, NK cells, and by subsets of cortical thymocytes or CD4+ T cells and involded in regulating receptor-mediated leucocyte signaling responses.Additional information: