CD44v6 Antibody, anti-human, APC, REAfinity™

01MT06208

Clone REA706 recognizes the CD44v6 antigen. CD44 is the receptor for hyaluronic acid (HA), which plays an important role in cell migration, tumor growth, and progression. CD44 is involved in the modification of the activity of receptors including MET and the ERBB family of tyrosine kinases. CD44 is a marker for many types of cancer stem cells (CSC), including breast CSCs that possess higher tumorigenicity and metastatic potential, colorectal, pancreatic, and prostate CSCs. In addition, expression was observed in several cancers as well as on carcinoma cell lines. Here, CD44 plays a role in can