CD366 (TIM-3) Antibody, anti-mouse, APC, REAlease®

01MT09314

Clone REAL168 is an antibody fragment derived from the full CD366 (TIM-3) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.Clone REAL168 recognizes the mouse CD366 (TIM-3) antigen, which is a Tʜ1-specific cell surface protein expressed by differentiated CD4+ Tʜ1 and CD8+ Tc1 cells and macrophages. It is absent on CD4+ Tʜ2 and CD8+ Tc2 cells. CD366 (TIM-3) has been proposed to inhibit Tʜ1-mediated immune responses. TIM-3 absence enhances the severity of exper