CD366 (TIM-3) Antibody, anti-human, APC

01MT16242

The monoclonal antibody F38-2E2 recognizes human cell surface molecule CD366 (TIM-3), which is expressed on activated T cells, especially Tʜ1 cells, monocytes, macrophages, and dendritic cells. CD366 (TIM-3) has been proposed to inhibit Tʜ1-mediated immune responses and regulates Tʜ1 and Tʜ17 cytokine secretion. The interaction of TIM-3 and its ligand galectin-9 induces apoptosis of Tʜ1 cells.