CD354 (TREM-1) Antibody, anti-human, PerCP-Vio® 700, REAfinity™

01MT01646

Clone REA213 recognizes the human CD354 (TREM-1), a 30 kDa member of the triggering receptors expressed on myeloid cells (TREM) family of cell surface receptors. TREM receptors are immunoglobulin 'superfamily' members and contain a single variable-type immunoglobulin domain. Human TREM cluster is located on chromosome 6p21. Expression of TREM-1 is found on the cell surface of myeloid cells such as neutrophils, monocytes, dendritic cells, and macrophages. TREM-1 signals via ITAM-containing adaptor DAP12 and serves as an amplifier of cell activation in response to triggers such as LPS. TREM-1 ac