CD314 (NKG2D) Antibody, anti-rat, APC, REAfinity™

01MT03535

Clone REA471 recognizes the rat CD314 antigen, a single-pass type II membrane homodimeric glycoprotein belonging to the C-type lectin-like receptor family, which is also known as NKG2-D type II integral membrane protein (NKG2D) or killer cell lectin-like receptor subfamily K member 1 (Klrk1). Rat CD314 is expressed in NK cells, and is strongly expressed in resting CD8+ and CD4+ T cells, but not by thymocytes or other hemopoietic cells. It functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at t